Try folding the pill into a treat like ground beef, a piece of a hot dog, or soft cheese. Denamarin has no known serious side-effects. 2 You liked it! The supplement combines S-Adenosylmethionine (SAM-e) and silybin to support the liver by increasing the levels of beneficial antioxidants, protecting liver cells from lysis, and regenerating liver cells.. The smallest of my cats is twice the size of your dog! The directions by Nutramax on the bottle give the dose size of 1/4 tablet for a dog up to 6 lbs (Charlie is 5 lbs). If Marin is used in conjunction with Denamarin, the two products should be administered 12 hours apart for best response. As far as pilling a cat, I'm guessing he's NOT eating at all on his own, correct? Something went wrong. But - the question may be moot anyway. I suppose I could get the regular pills and shove one down his throat first thing every morning - great way to start the day. But I fear any good from the Denamarin would be offset by the bad effects of concentrated sugar like a marshmallow - he weighs on 5 1/2 pounds and weight gain would be detrimental. They are sensitive to moisture and extreme heat and should NOT be split or crushed. Still, if you crush it up, the Milk thistle portion (Sybilin) will likely still be somewhat active and may still help a bit.. Do you know of a SAME product (perhaps a liquid) that is separate form the milk thistle? Denamarin, a patented liver health supplement for veterinary use only, combines the pure and stabilized salt of S-Adenosylmethionine with silybin-phosphatidylcholine complex in a scored chewable tablet. I'd also do a 3-4 day trial where you give the denamarin with food. Get it as soon as Fri, Feb 19. I first gave him just a lick of plain PB to be sure he would not reject it out of hand (he has never had it before). His reaction to this was to smell the food and walk away. I don't remember specific instructions about the denamarin but have just noticed its coated (as opposed to the new chewable version). (They also got antibiotics.) Disruption of the film or sugar coating on a drug may result in rapid degradation of the active ingredient and may also cause skin irritation in patients or carers. Big dogs probably gulp them or do minimal chewing. I then mixed it up into his regular breakfast and he ate it all. But if it is already time for the next dose, skip the missed one and continue with the regular schedule. Palmbob - if it should not be chewed up, why is it manufactured in such a large disk that is scored in the middle? For a dog I would think that tossing miniature marshmallows might work - toss one or two plain, then the loaded and immediately show another plain to distract from the taste of the loaded one. Do not split or crush the tablets. Anyway it is supposed to be given on an empty stomach. Charlie seems very healthy and I am trying very hard to trust the results of a couple of blood tests that say he is not or may potentially have a problem. On just 1/4 for 2 days, day 1 the diarrhea ret.! The number of chewable tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian. Report Discussion in 'Feline Health - (Welcome & Main Forum)' started by fligorio, Jun 14, 2017. I wish I only knew of this stuff is really effective or only part of hype that drug companies pass out - think how they push everyone to take their vitamin pills although studies say eating correctly is the way to go - not wasting money on pills which the body does not use as effectively as good food. Learn more about supporting the FDMB - click here, (You must log in or sign up to reply here. Yankee - thanks for the input of your experience. There are also Denamarin® Chewable Tablets marketed for dogs available. You can crush the tablet and mix it with a small amount of soft food such as yogurt, honey or jam. Thanks for explaining about where the SAME portion is activated. From the the manufacturer's web site: "For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. Small dogs seem to be more finicky than big dogs when it comes to eating. What dose of tylenol can you give a 15lb dog and what medication will reduce inflammation? The chewable tablets can be given to dogs of all sizes. It is a pretty effective product and very safe when administered properly... but if you want it to work well, it has to be swallowed whole, sorry. Administer the tablet in whole without crushing or splitting it. Denamarin for dogs is used for liver disease and liver damage. But it is the SAME product that has shown the most promise in clinical trials. Otherwise, just stop with this and wait and see. I thought maybe he would get some benefit from it if not all that the drug company claims. I'm not sure my dog even tastes stuff that is small enough to swallow. $25.99 $ 25. The process of boiling turned the water into the vapor and forced the molecules of air out from the can. Denamarin also provides a bioavailable form of silybin which supports oxidative balance. If you miss giving a dose, give it as soon as you remember. FREE shipping and the BEST customer service! He recently threw up with some small bits of blood - could this be an ulcer from the denamarin? Then I put down a small glob with the crushed med. Now with these chewable tablets he eats them right up like a treat! 99. (I did try crushing it in food before I tasted one, but he foamed at the mouth and eventually spit it all up with a lot of mucus.) After a course of antibiotics (in case there was an infection, although no signs of such) and several diagnostic tests (I do not want to go to ultrasound and liver biopsy now), a genetic liver shunt has been ruled out. How to Administer Denamarin Properly Supposedly they have a pork flavoring (must be pretty nasty). From the the manufacturer's web site: "For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. If absolutely necessary (as if we were treating a definite illness with a proven treatment) I will go the harder route, but at this point I am not convinced that this nutritional supplement will actually do much for him. You will need to open up his mouth and drop the pill in. I have taken Macy off Denamarin. Just to add final update - the Vet called me yesterday and we talked all this over. LOL! The larger the pet the larger the vet bills! I suppose I could get the pills and force one down his throat every morning. At this point I am ready to stop this whole thing, get him to eating well again, and use only the Canine Hepatic Support (which contains a little milk thistle, but no SAME and therefore less than ideal), and try again in a month or so. It apparently is a nutritional supplement supposed to support a healthy liver and to assist the liver in regeneration (I have no idea if this would really happen as so many drug companies promise so much - at least it promotes a healthy bottom line for their company!). So these chewables must be meant to be chewed and it apparently is okay to cut them up at least 3 or 4 days ahead (one gets cut into 4 little ones). If I give it to him in a bit of chicken, he eats the chicken, spits out the tiny lump of Denamarin, and looks at me. on Nutramax site to identify any binders that might be irritants. If I gave him nothing else all day, he finally ate it in the late afternoon. 10/10 recommend. Denamarin for Dogs High level nutritional support for the liver Description. That leaves several other possibilities. A few minutes later I put down his regular Merrick Terducken breakfast and he quickly ate it (showing he was hungry). But you can switch, with the advice of your vet, to standard milk thistle, liquid vitamin E and a B complex with C. The E and C enhance the effects of the milk thistle. This morning I tried again to do it right - took a tiny bit of cottage cheese (which Charlie likes) and added a crushed up dose of the Denamarin. When does he go for his next blood test? For the cats I gave a little ball of just flaver doh, then the loaded ball then another ball of plain. Denamarin tablets are available in three sizes: for cats and small dogs up to 12 lbs., for medium dogs 13-34 lbs., and for large dogs weighing more than 35 lbs. These medicines are designed to release an even amount of medicine over a specific period of time in the body. Denamarin is a supplement that can help your pet’s liver get back on the mend. Administer the tablet in whole without crushing or splitting it. She said her dog gobbles it up, but then went on to say he is a Lab and gobbles up everything in sight without tasting anything! Denamarin for Large Dogs: 425 mg. Just a quick note: Denamarin for dogs side effects is unknown… because they haven’t found any yet! I don't have any marshmallows as I detest them myself - but, of course, I could get some. Your veterinarian can evaluate the length of support needed through follow-up examinations, blood work, and/or other laboratory work. Still, if you crush it up, the Milk thistle portion (Sybilin) will likely still be somewhat active and may still help a bit.. Denamarin can be used in conjunction with Marin ® to provide additional silybin levels and the benefits of vitamin E and zinc supplementation. I was wondering if I could possibly dissolve it in some water and she can drink that (I'm thinking that I can't, because I've heard that it's time-released or something like that). Save 5% more with Subscribe & Save. 99. The coated one can't be broken or crushed because it needs that outer coat on the tablet to get it through the stomach, otherwise the drug will be broken down and inactivated before it … He looked at it, smelled it,and walked away. 2 Crushing these tablets therefore may not seriously affect how the drug is released but may cause the resultant mixture to be unpleasant to taste which is likely to negatively affect adherence. When I brought Charlie into our home back in August, I had no idea he was such an opinionated little fellow - he seems quite sensible about everything we have asked of him except this denamarin. We stopped the Denamarin & looked up ingred. 4.7 out of 5 stars 1,814. I will try again periodically with different foods, but don't expect much. I don't want to put him off of eating again - that can't be healthy for him. I understand why you are saying don't put it in his food. For the last several days I put it crushed in his breakfast food which he had been eating well (after several months of trying to find a quality food that he would eat well). Denamarin chewable tablets for Dogs of all sizes contain 225 mg S-Adenosylmethionine and 82 mg Silybin-phosphatidylcholine complex (SPC), providing 24 mg of Silybin A+B. These dogs can benefit from Denamarin to help with elevating liver enzymes and essential functions so that they are able to manage their condition. Something went wrong. I have tried cream cheese - no luck. Denamarin Side Effects. It can be given supposedly in a tiny bit of food if necessary. The supplement combines S-Adenosylmethionine (SAM-e) and silybin to support the liver by increasing the levels of beneficial antioxidants, protecting liver cells from lysis, and regenerating liver cells.. What I have is by Nutramax called Denamarin Chewable Tablets (not the earlier pills). It can be really hard to get your dog to swallow a pill, but if you try hiding it, you might have success. The first thing to consider is if the medication can be crushed in the first place. Final agreement was to back off - don't want to start an eating problem where he rejects all healthy food. The vet wants him to take Denamarin once a day. It was a daily struggle to get my French Bulldog, Kingsley, to swallow his Denamarin pill. OMG! Thank you! Denamarin should not be crushed, cut up, or dissolved in water. She suggested trying one last time using a glob of peanut butter (strong taste) with denamarin crushed up first thing in the morning when he is at his most hungry. Please try again later. The vet's office cut several of them on the score and again in half, producing 1/4 of each for giving a small dog. The tablets come in three different strengths; for cats and small dogs, for medium dogs, or for large dogs." But other specific dosage forms of medicines must be swallowed whole and are not safe to cut, crush, chew, or dissolve. Denamarin ® Advanced Chewable Tablets should be given on an empty stomach; however, if needed they can be administered with a small amount of food or treat. The Difference Between Denamarin and Denosyl | EntirelyPets - Liver disease is deadly if left untreated in pets. Some over-the-counter (OTC) medicines can be cut, crushed, chewed, opened, or dissolved prior to taking them. Maybe the Denamarin will do not as good given in a complete meal, but it certainly will not do any good sitting in the dish because he will not touch it. The number of chewable tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian. So apparently he simply does not like the denamarin. If they dissolve in the intestine, not the stomach, pilling and washing it down with water might be OK. It was a daily struggle to get my French Bulldog, Kingsley, to swallow his Denamarin pill. I opted for the chewable tablets that are formulated for a dogs taste buds but safe for cats, thinking I could crush it up and disguise it, but it's proving to be a great struggle to try to get the supplement into her. For a 5 lb dog it has to be cut in half and then cut again. He licked it fine - just a smear. Oftentimes people ask if crushing their pet’s medication up in their food is an option. First, you need to crush your dog’s pill into a fine powder. My cat has been prescribed Denamarin for liver support. In the absence of Denosyl, you can give your pet Denamarin as an alternative, but do not do so without talking to the vet first. He can just about swallow a hamburger whole and it takes him less that 10min to make the knuckle that comes out of a ham to disappear and be back looking at you and going "do you have more. https://staging-na01-1800petmeds.demandware.net/s/1800petmeds/Denamarin+Chewable+Tabs-prod438143.html. Absorption is better on an empty stomach. These Denamarin® tablets are enteric coated. Vet said to cont. I believe that you can crush the tablets without decreasing the effects. He looked at it, smelled it, and walked away. 2 You liked it! I would be happy to … This is getting to be a big issue for a product that you say has only "shown promise in clinical trials". One helpful way to support liver health is by adding the supplement Denamarin to your dog or cat’s diet. I gave the pill in a coating of Flavor Doh and then waited a bit to feed. I cannot explain the scoring, unless they have changed the formulation that allows it to be freed of its coating (most drugs with a coating have it for a reason-either it is because the product tastes like crap, or because it's supposed to be swallowed, protected from the stomach, and activated deeper in the intestinal tract). By heating up our can, we boiled the water inside it. Maybe having the stomach empty means it would be moved out faster. rice diet with a probiotic until stool was normal, thenramped her back to her reg. Storage. Even a large dog getting the whole product would probably chew it. It is a pretty effective product and very safe when administered properly... but if you want it to work well, it has to be swallowed whole, sorry. What should I text my crush in the morning? At home, watch for improvements in your pet’s attitude, appetite, and activity level. Well - I guess we are all allowed to be stubborn about a few things in life, even when it is not good for us! What do you think? You could also coat the pill in peanut butter, but make sure you choose a brand that’s free of xylitol, a sugar substitute that’s dangerous for dogs. While you can use a mortar and pestle, rolling pin or even a hammer; those of you who medicate your dog’s daily may find using a … This morning after that performance I put a bit of the regular food on a plate without the denamarin and he smelled it, looked at me, and then ate it up. My Toy Fox Terrier Charlie has come up with elevated liver enzymes - clinically appears very healthy. This was not good for several obvious reasons. and Over - 30 Tablets. Film or sugar-coated medicines. While … Denamarin for dogs or cats has no known serious side-effects. In emergency cases you can give meloxicam 0,1-0,2 mg/kg or metamizol i've been giving my dog denamarin and ursodiol by crushing and putting in his food. I planned to let him eat that and then wait an hour for his breakfast. By Jessica Vogelsang, DVM Getting a pet to take their meds is one of the great challenges in veterinary medicine, and difficulty in pilling is one of the number one causes of non-compliance. ... Denamarin Liver Support Supplements for Small Dogs (up to 12 lbs) and Cats. This wouldn't work with Denamarin because it tastes awful!! We cannot get it in her whole (we've tried pushing it down her throat and breaking it up in her food, but she won't eat it). Two of my cats took Denamarin for liver function - it is based on milk thistle which is a natural remedy for the liver. ). Hello! Denamarin is described as "a nutritional supplement containing the antioxidant Silybin used to improve your pet's liver function by increasing liver glutathione levels. I believe that you can crush the tablets without decreasing the effects. Use of this Web site constitutes acceptance of the Davesgarden.com. Denamarin is best absorbed if given on an empty stomach, about one hour before the first meal in the morning [4]. I would be happy to contact Nutramax directly for you and ask about this. Each one is the size of very thick nickel and is scored across the middle. Save 5% more with Subscribe & Save. 10/10 recommend. He will not be tested again until June or so.